SELECTED PUBLICATIONS
Springstein BL, Paulo JA, Park H, Henry K, Fleming E, Feder Z, Harper JW, Hochschild A. Systematic analysis of nonprogrammed frameshift suppression in E. coli via translational tiling proteomics. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2317453121. doi: 10.1073/pnas.2317453121.
Jager K, Orozco-Hidalgo MT, Springstein BL, Joly-Smith E, Papazotos F, McDonough E, Fleming E, McCallum G, Yuan AH, Hilfinger A, Hochschild A, Potvin-Trottier L. Measuring prion propagation in single bacteria elucidates a mechanism of loss. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2221539120. doi: 10.1073/pnas.2221539120.
Springstein BL, Deighan P, Grabe GJ, Hochschild A. A Bacterial Cell-Based Assay To Study SARS-CoV-2 Protein-Protein Interactions. mBio. 2021 Dec 21;12(6):e0293621. doi: 10.1128/mBio.02936-21.
Fleming E, Yuan AH, Heller DM, Hochschild A. A bacteria-based genetic assay detects prion formation. Proc Natl Acad Sci. 2019 Feb; pii: 201817711. doi: 10.1073/pnas.1817711116.
McPartland L, Heller DM, Eisenberg DS, Hochschild A*, Sawaya MR*. Atomic Insights into the genesis of cellular filaments by globular proteins. Nat Struct Mol Biol. 2018 Aug; 25(8):705-714.
Yuan AH, Hochschild A. A bacterial global regulator forms a prion. Science 2017; 355:198-201.
Berry KE, Hochschild A. A bacterial three-hybrid assay detects Escherichia coli Hfq-sRNA interactions in vivo. Nucleic Acids Res 2017; doi: 10.1093/nar/gkx1086
Heller DM, Tavag M, Hochschild A. CbtA toxin of Escherichia coli inhibits cell division and cell elongation via direct and independent interactions with FtsZ and MreB. PLoS Genet 2017; 13(9):e1007007
Goldman SR, Nair NU, Wells CD, Nickels BE, Hochschild A. The primary sigma factor can access the transcription elongation complex from solution in vivo. eLife 2015, 4: e10514.
Yuan AH, Garrity SJ, Nako E, Hochschild A. Prion propagation can occur in a prokaryote and requires the ClpB chaperone. eLife 2014; 3: e02949.
Sivanathan V and Hochschild A. Generating extracellular amyloid aggregates using E. coli cells. Genes Dev 2012; 26:2659-2667.
