Seth Darst - Rockefeller University
Ian Dodd & Barry Egan - University of Adelaide
Richard Ebright - Rutgers University
Debbie Hinton - NIH
Mitch Lewis - U Penn School of Medicine
Jeff Roberts - Cornell University)
Konstantin Severinov - Rutgers University

Nickels BE, Roberts CW, Roberts JW, and Hochschild A. RNA-mediated destabilization of the σ⁷⁰ region 4/ß flap interaction facilitates engagement of RNA polymerase holoenzyme by the Q antiterminator. Mol. Cell 2006; 24: 457-468.

Pinkett HW, Shearwin KE, Stayrook S, Dodd IB, Burr T, Hochschild A, Egan JB, Lewis M. The structural basis of cooperative regulation at an alternate genetic switch. Mol. Cell 2006; 21:605-15.

Deaconescu AM, Chambers AL, Smith AJ, Nickels BE, Hochschild A, Savery NJ, Darst SA. Structural basis for bacterial transcription-coupled DNA repair. Cell 2006; 124:507-20.

Nickels BE, Garrity SJ, Mekler V, Minakhin L, Severinov K, Ebright RH, Hochschild A. The interaction between σ⁷⁰ and the ß-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation. Proc. Natl. Acad. Sci. USA 2005; 102:4488-93.

Nickels BE, Mukhopadhyaya J, Garrity SJ, Ebright RH, and Hochschild A. The σ⁷⁰ subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter. Nat. Struct. Mol. Biol. 2004; 11: 544-550.

Gregory BD, Nickels BE, Garrity SJ, Severinova E, Minakhin L, Bieber-Urbauer RJ, Urbauer JL, Heyduk T, Severinov K, and Hochschild A. A regulator that inhibits transcription by targeting an inter-subunit interaction of RNA polymerase holoenzyme. Proc. Natl. Acad. Sci. USA 2004; 101:4554-4559.

Dodd IB, Shearwin KE, Perkins AJ, Burr T, Hochschild A, and Egan JB. Cooperativity in long-range gene regulation by the λ CI repressor. Genes Dev. 2004; 18:344-354.

Jain D, Nickels BE, Sun L, Hochschild A, and Darst SA. Structure of a ternary transcription activation complex. Mol. Cell 2004; 13:45-53.

Nickels BE, Dove SL, Murakami KS, Darst SA, and Hochschild A. Protein-protein and protein-DNA interactions of σ⁷⁰ region 4 involved in transcription activation by λcI. J. Mol. Biol. 2002, 324; 17-34.

Nickels BE, Roberts CW, Sun H, Roberts JW, and Hochschild A. The σ⁷⁰ subunit of RNA polymerase is contacted by the λQ antiterminator during early elongation. Mol. Cell 2002; 10: 611-622.

Pande S, Makela A, Dove SL, Nickels BE, Hochschild A, and Hinton DM. The bacteriophage T4 transcription activator MotA interacts with the far-C-terminal region of the σ⁷⁰ subunit of Escherichia coli RNA polymerase. J. Bacteriol. 2002; 184: 3957-3964.